RyanAir fly from Stanstead to Brindisi, 50km from Lecce, the capital
of Salento. Another RyanAir destination, Bari, is a further 100km up
the coast. BA also fly low-cost from Gatwick to Bari.

Boats to Greece leave from both Bari and Brindisi.

Rome and Naples are both roughly six hours away, by road or rail.